Table 1 Enzymes present in the rat liver but not in the human liver.
From: Genome-scale metabolic model of the rat liver predicts effects of diet restriction
Gene symbol | Enzyme | Enzyme name | Reaction formula | Pathway | Ref. |
|---|---|---|---|---|---|
Tdh | 1.1.1.103 | L-threonine 3-dehydrogenase | L-threonine + NAD+ = L-2-amino-3-oxobutanoate + NADH + H+ | Glycine, serine and threonine metabolism | |
Gulo | 1.1.3.8 | L-gulonolactone oxidase | L-gulono-1,4-lactone + O2 = L-ascorbate + H2O2 | Ascorbate and aldarate metabolism | |
Cmah | 1.14.18.2 | CMP-N-acetylneuraminate monooxygenase | CMP-N-acetylneuraminate + 2 ferrocytochrome b5 + O2 + 2 H+ = CMP-N-glycoloylneuraminate + 2 ferricytochrome b5 + H2O | Amino sugar and nucleotide sugar metabolism | |
Uox | 1.7.3.3 | uric acid oxidase | urate + O2 + H2O = 5-hydroxyisourate + H2O2 | Purine metabolism | |
Ggta1 | 2.4.1.87 | N-acetyllactosaminide 3-alpha-galactosyltransferase | UDP-alpha-D-galactose + beta-D-galactosyl-(1->4)-beta-N-acetyl-D-glucosaminyl-R = UDP + alpha-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-N-acetylglucosaminyl-R (where R can be OH, an oligosaccharide or a glycoconjugate) | Glycosphingolipid biosynthesis - lacto and neolacto series | |
Art2b | 3.2.2.5 | NAD glycohydrolase | NAD+ + H2O = ADP-D-ribose + nicotinamide | Nicotinate and nicotinamide metabolism | |
RGD1309350 | 3.5.2.17 | hydroxyisourate hydrolase | 5-hydroxyisourate + H2O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate | Purine metabolism | |
LOC688286 | 4.1.2.48 | low-specificity L-threonine aldolase | L-threonine = glycine + acetaldehyde | Glycine, serine and threonine metabolism |
