Table 4 Overall and region-based detection rate using single T1 sequence MRI evaluation.

From: Accuracy of standard clinical 3T prostate MRI for pelvic lymph node staging: Comparison to 68Ga-PSMA PET-CT

Single T1

N

Sensitivity + 95% CI

Specificity + 95% CI

PPV + 95 95% CI

NPV + 95% CI

All LN

130/187

71.8%

(58.2–82.3%)

99.0%

(98.3–99.5%)

72.2%

(47.9–88.0%)

99.5%

(98.5–99.8%)

Iliac left

21/31

73.1%

(48.9–88.5%)

99.0%

(97.1–99.6%)

53.9%

(19.5–83.1%)

99.6%

(98.1–99.9%)

Iliac right

28/47

65.0%

(43.2–81.9%)

98.0%

(95.2–99.2%)

71.7%

(38.2–92.4%)

98.7%

(98.7–99.7%)

Obturator left

24/33

75.9%

(50.0–91.0%)

99.7%

(98.3–99.8%)

98.4%

(86.0–99.6%)

98.2%

(85.9–99.6%)

Obturator right

36/52

67.5%

(47.2–83.0%)

97.8%

(95.0–99.0%)

86.2%

(65.0–97.1%)

93.5%

(86.6–98.9%)

Presacral

13/16

82.3%

(48.8–95.8%)

100%

(100–100%)

99.9%

(0–100%)

97.0%

(0–100%)

Inguinal

8/8

100%

(0–100%)

99.3%

(0–100%)

28.5%

(18.4–36.6%)

100%

(100–100%)

  1. This table summarizes the region-based analysis of the lymph node metastases in MRI using single T1 sequence evaluation. The columns present number, sensitivities, specificities, positive and negative predictive value including 95% confidence interval. The rows are fielded in the six defined anatomical regions iliac left and right, obturator left and right, presacral and inguinal region.
  2. Abbreviations: LN = Lymph nodes, N = number of positive LN in MRI versus PET-CT, PPV = positive predictive value, NPV = Negative predictive value, CI = 95% Confidence interval.
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