Figure 3 | Scientific Reports

Figure 3

From: Transcription Factors Regulation in Human Peripheral White Blood Cells during Hypobaric Hypoxia Exposure: an in-vivo experimental study

Figure 3

Box and Whisker plots show the marked effects of hypobaric hypoxia exposure (3830 m) on ROS production and relative biomarkers of oxidative damage. Direct 24 h exposure to HH induces marked increases in ROS, TBARS, 8-isoPGF α, 8-OHdG, PC and concomitant reduction in TAC. After 72 h of exposure to hypoxia there is a partial recover of the basal conditions with a slight improve of the TAC and a reduction of ROS and cellular damages amounts. The median (continuous band) and the mean (dotted band) are represented inside the boxes. *P < 0.05 and **P < 0.001 after Bonferroni correction.

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