Figure 3

Heart rate regulation and physical activity. (a) Heart rate of control and hEHT animals following implantation of the hEHTs (day 10–day 35, data are averaged over 12 h and are given as mean ± SEM). (b) Average heart rates following implantation of the EHTs (day 10–day 35, lines and error bars denote mean ± SEM). (c) Physical activity of control and hEHT animals following implantation of the hEHTs (day 10–day 35, data are averaged over 12 h and are given as median ± interquartile range, arbitrary units, A.U.). (d) Average physical activity (arbitrary units, A.U., day 10–day 35, lines denote median and whiskers represent min to max). (a–d) Results were not statistically significantly different between the groups using a parametric (b) and an unparametric (d, Mann-Whitney test) unpaired Student’s t-test. Grey zones (a,c) indicate postoperative period recordings (48 h) which were excluded from analysis. Ctrl, animals implanted with cell-free fibrin constructs (n = 8); hEHT, animals with implanted hEHTs (n = 10).