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Figure 1

From: Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia

Figure 1

svPPA Network. Network results are shown for protein interaction network based pathway analysis (PINBPA) in the semantic variant of primary progressive aphasia compared to controls. The network genes are color coded according to their respective p-value (see Methods), with warmer colors indicating p-values closer to the minimum value of 1.89E-4 and cooler colors indicating p-values closer to the maximum p-value of 0.05. The size of a node corresponds to closeness centrality (a metric that describes a node’s nearness to other network nodes). The thickness of edges in the network corresponds to edge betweenness (a metric that describes the number of paths going through an edge in the network).

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