Figure 7
FACS analysis of intracellular ROS by H2DCFDA (a), of mitochondrial \({{\rm{O}}}_{2}^{\cdot -}\) production by MitoSOX (b) and of cellular lipid peroxidation by BODIPY-581/591-C11, evaluated at 1 h (open columns) and 2 h (striped columns) and expressed as percent changes of the untreated controls. All these parameters were enhanced upon H + R and significantly reduced by MnQ2 and MnM2. At the shorter time point (1 h), MnQ2 was significantly more effective than MnM2. ***p < 0.001 vs. controls, MnM2 and MnQ2; (one-way ANOVA); #p < 0.05, n.s. not significant vs. MnM2 (Student’s t test).
