Figure 8 | Scientific Reports

Figure 8

From: Different Antioxidant Efficacy of Two MnII-Containing Superoxide Anion Scavengers on Hypoxia/Reoxygenation-Exposed Cardiac Muscle Cells

Figure 8

FACS analysis of mitochondrial activity by RSZ (a), of mitochondrial membrane potential (Δψ) by TMRM (b) and of mitochondrial transition pore opening (mPTP) by extinction of calcein fluorescence, evaluated at 1 h (open columns) and 2 h (striped columns) and expressed as percent changes of the untreated controls. All these parameters were decreased by H + R and significantly increased by MnM2 and MnQ2. At the shorter time point (1 h), MnQ2 was more effective than MnM2. ***p < 0.001 vs. controls, MnM2 and MnQ2; (one-way ANOVA); #p < 0.05, n.s. not significant vs. MnM2 (Student’s t test).

Back to article page