Figure 1
(A) T2-weighted anatomical image with distance to Bregma and primary somatosensory. Hindlimb cortex contralateral to the stimulated paw (S1HL) indicated. (B) Statistical parametric maps of BOLD signal changes (ΔBOLD) elicited by electrical hindpaw stimulation at 1, 2, and 3 mA for N = 5 animals (for 1 mA) and N = 6 animals (for 2 mA and 3 mA). Maps are shown as color-coded beta-values. (C) Average signal time courses per stimulation amplitude show stimulus-evoked ΔBOLD extracted from the contralateral and ipsilateral S1HL (mean +− standard deviation). Note that contra- and ipsilateral signal changes look almost identical. The gray rectangle indicates the stimulation period after a baseline period of 720 repetitions (s). (D) Correlation values R2 between contra- and ipsilateral responses are given in the plots for the maximum ΔBOLD amplitude values and for the integral of the contra- and ipsilateral stimulus-evoked signal changes in the first 720 repetitions (s) after stimulus onset. Different current amplitudes are indicated by colours. Data points represent individual animals.
