Table 2 Marginal estimates (95% CI) of hippocampal subfield volumes across immediate recall (IR) and delayed recall (DR) scores, with age effects.

From: Dissociable age and memory relationships with hippocampal subfield volumes in vivo:Data from the Irish Longitudinal Study on Ageing (TILDA)

IR model

DR model

IR score:

4

5.5

7

8.5

10

DR score:

0

2

4

6

8

10

Subfield

Subfield

CA2/3

195.49 (185.20, 205.78)

207.16 (203.13, 211.18)

204.06 (201.50, 206.63)

200.73 (197.38, 204.08)

211.66 (202.54, 220.77)

CA2/3

188.04 (174.43, 201.65)

200.8 (195.14, 206.47)

205.34 (201.37, 209.31)

205.04 (202.38, 207.71)

203.29 (200.13, 206.45)

203.46 (197.93, 208.98)

CA4

238.67 (229.76, 247.57)

243.82 (240.32, 247.32)

241.12 (238.91, 243.33)

239.74 (236.83, 242.65)

248.87 (240.98, 256.75)

CA4

230.99 (219.19, 242.78)

240.38 (235.45, 245.32)

242.66 (239.21, 246.11)

241.53 (239.23, 243.83)

240.74 (238.00, 243.47)

243.99 (239.20, 248.79)

GC-DG

280.82 (271.63, 290.02)

285.54 (281.93, 289.15)

281.68 (279.39, 283.96)

279.33 (276.33, 282.33)

288.60 (280.46, 296.75)

GC-DG

271.76 (259.59, 283.94)

283.00 (277.91, 288.08)

284.94 (281.39, 288.50)

282.40 (280.02, 284.77)

280.16 (277.33, 282.98)

283.02 (278.07, 287.96)

Presubic.

288.56 (273.70, 303.43)

287.26 (281.50, 293.03)

288.11 (284.39, 291.82)

289.78 (284.97, 294.59)

290.96 (277.80, 304.13)

Presubic.

295.39 (275.81, 314.98)

291.75 (283.66, 299.85)

288.18 (282.48, 293.87)

286.29 (282.44, 290.15)

287.73 (283.18, 292.28)

294.11 (286.15, 302.07)

Subiculum

414.46 (399.76, 429.17)

413.52 (407.82, 419.22)

409.18 (405.51, 412.86)

406.40 (401.64, 411.16)

410.14 (397.11, 423.16)

Subiculum

408.75 (389.36, 428.15)

413.08 (405.06, 421.10)

412.39 (406.75, 418.04)

409.54 (405.72, 413.35)

407.34 (402.83, 411.84)

408.62 (400.74, 416.51)

CA1

619.49 (599.14, 639.84)

627.4 (619.55, 635.26)

613.44 (608.35, 618.53)

602.52 (595.96, 609.09)

619.56 (601.54, 637.58)

CA1

597.09 (570.33, 623.86)

624.97 (613.94, 636.00)

626.67 (618.90, 634.45)

615.56 (610.28, 620.84)

605.00 (598.78, 611.22)

608.34 (597.46, 619.22)

Mol. layer

542.20 (527.64, 556.75)

548.28 (542.64, 553.93)

539.71 (536.07, 543.34)

533.16 (528.45, 537.87)

545.34 (532.45, 558.23)

Mol. layer

530.88 (511.71, 550.06)

547.18 (539.25, 555.11)

547.65 (542.07, 553.23)

540.66 (536.89, 544.44)

534.60 (530.15, 539.06)

537.84 (530.05, 545.64)

Hipp. tail

486.84 (466.04, 507.63)

493.39 (485.36, 501.42)

493.91 (488.71, 499.12)

490.03 (483.32, 496.74)

483.37 (464.95, 501.78)

Hipp. tail

493.85 (466.44, 521.25)

489.65 (478.36, 500.94)

489.94 (481.98, 497.90)

492.04 (486.63, 497.44)

493.25 (486.88, 499.62)

490.89 (479.75, 502.03)

Parasubic.

61.49 (49.21, 73.77)

60.30 (55.52, 65.08)

61.31 (58.25, 64.38)

63.61 (59.63, 67.60)

66.27 (55.40, 77.14)

Parasubic.

63.61 (47.39, 79.83)

60.82 (54.10, 67.54)

59.93 (55.20, 64.65)

60.70 (57.51, 63.88)

62.90 (59.14, 66.67)

66.31 (59.72, 72.90)

HATA

57.72 (46.12, 69.32)

59.32 (54.80, 63.84)

61.47 (58.58, 64.36)

63.30 (59.53, 67.06)

63.90 (53.63, 74.18)

HATA

53.68 (38.31, 69.04)

58.51 (52.14, 64.89)

60.34 (55.87, 64.82)

60.96 (57.95, 63.97)

62.16 (58.59, 65.72)

65.73 (59.49, 71.97)

Fimbria

81.84 (68.25, 95.43)

78.32 (73.04, 83.59)

79.52 (76.13, 82.92)

83.13 (78.73, 87.53)

86.80 (74.77, 98.83)

Fimbria

73.35 (55.38, 91.33)

78.69 (71.25, 86.13)

80.03 (74.80, 85.26)

79.93 (76.39, 83.46)

80.95 (76.77, 85.13)

85.66 (78.35, 92.97)

Age:

50

60

70

80

 

Age:

50

60

70

80

  

Subfield

Subfield

CA2/3

205.09 (194.55, 215.64)

205.31 (201.88, 208.73)

203.91 (201.42, 206.39)

200.89 (196.27, 205.52)

 

CA2/3

205.13 (194.55, 215.71)

205.07 (201.63, 208.50)

203.84 (201.35, 206.33)

201.45 (196.83, 206.07)

  

CA4

246.75 (237.61, 255.89)

245.70 (242.71, 248.69)

241.62 (239.48, 243.77)

234.52 (230.47, 238.58)

 

CA4

246.94 (237.76, 256.12)

245.47 (242.47, 248.47)

241.53 (239.38, 243.68)

235.11 (231.06, 239.17)

  

GC-DG

293.64 (284.21, 303.08)

290.25 (287.17, 293.32)

281.93 (279.71, 284.15)

268.69 (264.52, 272.86)

 

GC-DG

294.22 (284.75, 303.69)

290.09 (287.00, 293.18)

281.78 (279.56, 284.01)

269.29 (265.12, 273.46)

  

Presubic.

298.04 (282.86, 313.23)

296.96 (292.09, 301.83)

288.95 (285.35, 292.55)

274.00 (267.46, 280.55)

 

Presubic.

298.35 (283.14, 313.56)

297.20 (292.32, 302.07)

288.95 (285.34, 292.55)

273.61 (267.09, 280.13)

  

Subiculum

413.04 (398.02, 428.07)

420.32 (415.5, 425.14)

411.42 (407.85, 414.98)

386.33 (379.85, 392.8)

 

Subiculum

413.46 (398.39, 428.52)

420.14 (415.31, 424.97)

411.29 (407.72, 414.86)

386.92 (380.45, 393.38)

  

CA1

632.95 (612.19, 653.71)

630.61 (623.99, 637.24)

613.94 (609.00, 618.88)

582.92 (574.05, 591.80)

 

CA1

634.80 (614.02, 655.58)

630.20 (623.58, 636.82)

613.49 (608.55, 618.43)

584.67 (575.84, 593.51)

  

Mol. layer

568.91 (554.04, 583.79)

560.86 (556.08, 565.63)

539.54 (536.02, 543.07)

504.97 (498.56, 511.38)

 

Mol. layer

570.11 (555.21, 585.00)

560.68 (555.90, 565.45)

539.28 (535.75, 542.81)

505.91 (499.52, 512.30)

  

Hipp. tail

517.47 (496.26, 538.69)

515.56 (508.79, 522.33)

492.92 (487.87, 497.97)

449.54 (440.47, 458.61)

 

Hipp. tail

515.70 (494.43, 536.97)

515.02 (508.25, 521.80)

493.11 (488.06, 498.17)

449.97 (440.93, 459.02)

  

Parasubic.

51.57 (39.01, 64.13)

56.02 (51.97, 60.07)

62.56 (59.59, 65.53)

71.18 (65.73, 76.64)

 

Parasubic.

51.61 (39.00, 64.21)

56.10 (52.04, 60.16)

62.57 (59.59, 65.55)

71.02 (65.57, 76.47)

  

HATA

56.46 (44.59, 68.33)

58.44 (54.6, 62.28)

61.80 (58.99, 64.61)

66.55 (61.37, 71.72)

 

HATA

56.46 (44.52, 68.40)

58.42 (54.56, 62.27)

61.80 (58.98, 64.61)

66.60 (61.42, 71.77)

  

Fimbria

77.78 (63.89, 91.67)

82.05 (77.58, 86.51)

81.75 (78.46, 85.04)

76.88 (70.87, 82.88)

 

Fimbria

78.50 (64.54, 92.46)

82.17 (77.69, 86.65)

81.64 (78.34, 84.95)

76.93 (70.92, 82.93)

  
  1. Marginal estimates adjusted for sex, education, total brain grey matter volume, handedness, smoking, and cardiovascular disease history. Bold text - significant non-linear effects in fully-adjusted model
  2. (p < 0.05); italicised text - marginal linear/non-linear coefficients in fully-adjusted model (p < 0.08); see Table 3. See Supplementary Tables 1 and 2 for IR and DR full model outputs, respectively.