Table 2 Univariable regression model for prediction of cardiac mortality based on the derivation cohort.

Age (years)

<0.001

<0.001

<0.001

<40

1.00 (reference)

1.00 (reference)

1.00 (reference)

40–59

2.95 (1.08–8.00)

2.64 (1.08–6.47)

3.21 (1.31–7.85)

60–69

5.21 (1.91–14.22)

4.27 (1.73–10.53)

5.86 (2.39–14.38)

70–79

12.53 (4.60–34.14)

10.59 (4.30–26.08)

14.04 (5.72–34.45)

> = 80

21.75 (7.89–59.95)

18.11 (7.26–45.15)

23.59 (9.50–58.60)

Gender

<0.001

<0.001

<0.001

Male

1.00 (reference)

1.00 (reference)

1.00 (reference)

Female

2.52 (2.05–3.09)

2.42 (1.98–2.96)

2.48 (2.07–2.98)

Ethnicity

0.105

0.105

0.072

Chinese

1.00 (reference)

1.00 (reference)

1.00 (reference)

Malay

1.01 (0.80–1.27)

1.05 (0.84–1.31)

1.09 (0.90–1.33)

Indian

0.77 (0.59–1.01)

0.77 (0.59–1.01)

0.77 (0.61–0.98)

Others

1.52 (0.85–2.73)

1.44 (0.80–2.57)

1.23 (0.70–2.15)

History of diabetes

<0.001

<0.001

<0.001

No

1.00 (reference)

1.00 (reference)

1.00 (reference)

Yes

2.10 (1.74–2.52)

1.98 (1.66–2.37)

2.18 (1.86–2.57)

History of hypertension

<0.001

<0.001

<0.001

No

1.00 (reference)

1.00 (reference)

1.00 (reference)

Yes

1.75 (1.45–2.12)

1.75 (1.45–2.10)

2.01 (1.70–2.38)

History of dyslipidemia

0.168

0.316

0.002

No

1.00 (reference)

1.00 (reference)

1.00 (reference)

Yes

1.14 (0.95–1.36)

1.09 (0.92–1.31)

1.28 (1.09–1.50)

History of IHD

0.014

0.011

<0.001

No

1.00 (reference)

1.00 (reference)

1.00 (reference)

Yes

1.34 (1.06–1.70)

1.34 (1.07–1.69)

1.75 (1.44–2.12)

Current smoker

<0.001

<0.001

<0.001

No

1.00 (reference)

1.00 (reference)

1.00 (reference)

Yes

0.53 (0.43–0.64)

0.61 (0.50–0.74)

0.59 (0.49–0.70)

BMI (kg/m²)

0.057

0.026

0.016

< = 23

1.00 (reference)

1.00 (reference)

1.00 (reference)

>23

0.80 (0.63–1.01)

0.78 (0.62–0.97)

0.79 (0.65–0.96)

Killip class on admission

<0.001

<0.001

<0.001

I

1.00 (reference)

1.00 (reference)

1.00 (reference)

II

2.12 (1.36–3.31)

2.33 (1.55–3.51)

2.27 (1.59–3.25)

III

7.88 (5.68–10.92)

7.66 (5.59–10.52)

7.52 (5.64–10.02)

IV

15.24 (12.31–18.87)

13.58 (11.03–16.73)

11.58 (9.55–14.05)

Cardiac arrest in ambulance/on admission

<0.001

<0.001

<0.001

No

1.00 (reference)

1.00 (reference)

1.00 (reference)

Yes

12.87 (10.05–16.50)

11.07 (8.65–14.18)

9.37 (7.37–11.91)

Anterior STEMI

0.001

<0.001

<0.001

No

1.00 (reference)

1.00 (reference)

1.00 (reference)

Yes

1.37 (1.14–1.65)

1.44 (1.21–1.72)

1.37 (1.16–1.60)

Creatinine on admission (µmol/L)

<0.001

<0.001

<0.001

<70

1.00 (reference)

1.00 (reference)

1.00 (reference)

70–105

1.26 (0.83–1.92)

1.23 (0.83–1.82)

1.11 (0.80–1.55)

106–140

4.83 (3.19–7.33)

4.57 (3.09–6.75)

3.82 (2.74–5.33)

141–176

10.87 (6.87–17.20)

9.59 (6.19–14.87)

8.02 (5.47–11.76)

177–353

17.71 (11.15–28.14)

15.10 (9.69–23.52)

13.08 (8.85–19.31)

> = 354

9.68 (5.43–17.26)

7.99 (4.53–14.10)

9.50 (5.87–15.37)

Hemoglobin on admission (g/dL)

<0.001

<0.001

<0.001

<10

1.00 (reference)

1.00 (reference)

1.00 (reference)

11–11

0.86 (0.57–1.31)

0.84 (0.55–1.27)

0.78 (0.53–1.15)

12–13

0.36 (0.24–0.53)

0.34 (0.23–0.50)

0.32 (0.23–0.46)

14–16

0.16 (0.11–0.23)

0.16 (0.11–0.23)

0.14 (0.10–0.21)

> = 17

0.14 (0.09–0.21)

0.16 (0.11–0.25)

0.14 (0.10–0.21)

Elevated first troponin T/I on admission

<0.001

<0.001

<0.001

No

1.00 (reference)

1.00 (reference)

1.00 (reference)

Yes

2.08 (1.72–2.52)

2.11 (1.75–2.54)

2.15 (1.82–2.54)

S2B (minutes)

0.534

0.287

0.178

< = 180

1.00 (reference)

1.00 (reference)

1.00 (reference)

>180

1.06 (0.88–1.29)

1.11 (0.92–1.34)

1.12 (0.95–1.33)

Lowest LVEF during hospitalization (%)

<0.001

<0.001

<0.001

<40

1.00 (reference)

1.00 (reference)

1.00 (reference)

40–50

0.12 (0.09–0.17)

0.14 (0.11–0.19)

0.15 (0.12–0.19)

>50

0.10 (0.07–0.15)

0.10 (0.06–0.14)

0.12 (0.09–0.16)