Figure 2 | Scientific Reports

Figure 2

From: Fast dose fractionation using ultra-short laser accelerated proton pulses can increase cancer cell mortality, which relies on functional PARP1 protein

Figure 2

Cell survival dependency to the variation of the bunch repetition rate. Normalized survival fraction resulting from exposure for a given dose of LDP bunches delivered with different delay ranging from three to 60 seconds. Radioresistant Glioblastoma cell lines SF763 (triangles) (A) and U87-MG (dots) (B) were submitted to a dose corresponding to nine bunches of LDP (6.3 ± 1.39 Gy). (C) radiosensitive colorectal cancer HCT116 cells, WT (white squares) and p53−/− (black squares) were exposed to five bunches of LDP (3.5 ± 0.77 Gy). Each data point represents the mean and SD of three replicates obtained in at least three independent experiments.

Back to article page