Figure 2 | Scientific Reports

Figure 2

From: Poorly controlled diabetes during pregnancy and lactation activates the Foxo1 pathway and causes glucose intolerance in adult offspring

Figure 2

IPGTT. (A,B) Blood glucose levels during the IPGTT (left) and areas under the curve (AUC) (right) in male (A) and female offspring (B) at 7, 14, and 25 weeks. Blood glucose levels were measured after intraperitoneal injection of glucose (1 g/kg body weight). The numbers of male animals used in (A) are: 7 weeks, CTR offspring, n = 7 and STZ offspring, n = 6; 14 weeks, CTR offspring, n = 7 and STZ offspring, n = 6; 25 weeks, CTR offspring, n = 7 and STZ offspring, n = 6. The numbers of female animals used in (B) are: 7weeks, CTR offspring, n = 7 and STZ offspring, n = 6; 14 weeks, CTR offspring, n = 7 and STZ offspring, n = 6; 25 weeks, CTR offspring, n = 6 and STZ offspring, n = 6). Data represent the mean ± SE. *P < 0.05, **P < 0.01, N.S. not significant.

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