Table 2 Outcome parameters pre- and post- propensity score matching*.

From: Anti-androgenic therapy with finasteride in patients with chronic heart failure - a retrospective propensity score based analysis

 

unmatched cohort (total n = 1041)

matched cohort (total n = 328)

control group

(total n = 868)

treatment group

(total n = 173)

p value

ATT (95% confidence intervall)

control group

(total n = 164)

treatment group

(total n = 164)

p value

ATT (95% confidence intervall)

(Ln)NT-proBNP [ng/l]

7.1 ± 1.7 (n = 168)

6.9 ± 1.6 (n = 41)

0.588

−0.2 (−0.7 to 0.4)

7.5 ± 1.9 (n = 34)

6.8 ± 1.6 (n = 39)

0.087

−0.7 (−1.5 to 0.1)

Ejection fraction [%]

47.8 ± 14.7 (n = 354)

46.2 ± 13.4 (n = 70)

0.400

−1.6 (−5.3 to 2.2)

46.8 ± 16.5 (n = 68)

45.6 ± 13.4 (n = 66)

0.641

−1.2 (−6.4 to 3.9)

IVS [mm]

12.9 ± 2.3 (n = 464)

12.6 ± 2.2 (n = 122)

0.385

−0.2 (−0.7 to 0.2)

13.3 ± 2.4 (n = 93)

12.6 ± 2.1 (n = 114)

0.029

−0.7 (−1.3 to −0.1)

LVEDD [mm]

53.6 ± 8.5 (n = 540)

54.4 ± 8.1 (n = 141)

0.164

0.8 (−0.8 to 2.4)

52.6 ± 9.0 (n = 109)

54.6 ± 8.0 (132)

0.131

2.1 (−0.7 to 4.2)

LA-PLAX [mm]

45.2 ± 7.4 (n = 168)

44.9 ± 7.8 (n = 140)

0.463

−0.2 (−1.6 to 1.2)

45.0 ± 7.6 (n = 96)

44.8 ± 7.8 (n = 131)

0.554

−0.2 (−2.2 to 1.8)

QRS duration [ms]

120.0 ± 69.6 (n = 391)

123.1 ± 31.7 (n = 145)

0.010

3.0 (−8.7 to 14.8)

117.4 ± 27.7 (n = 72)

123.5 ± 31.9 (n = 137)

0.137

6.2 (−2.6 to 14.9)

QT duration [ms]

411.8 ± 49.7 (n = 244)

413.8 ± 58.8 (n = 135)

0.794

1.9 (−9.3 to 13.1)

420.5 ± 40.8 (n = 45)

417.2 ± 52.2 (n = 127)

0.396

−3.3 (−20.2 to 13.7)

QTc duration [ms]

448.7 ± 190.6 (n = 251)

443.9 ± 54.8 (n = 140)

0.249

−4.8 (−37.2 to 27.6)

445.2 ± 45.3 (n = 47)

446.5 ± 48.6 (n = 132)

0.858

1.4 (−14.6 to 17.4)

  1. *LV dimensions normalized to BSA are provided in Table S2 in the Data Supplement. Abbreviation: ATT = average treatment effect on the treated, IVS = Interventricular septum, LA-PLAX = Left atrium in parasternal long axis, LVEDD = Left ventricular enddiastolic diameter.