Figure 8 | Scientific Reports

Figure 8

From: Atomistic mechanisms underlying the activation of the G protein-coupled sweet receptor heterodimer by sugar alcohol recognition

Figure 8

(A) The T1R2 (pink) and T1R3 (green) monomers comprising amino acid residues within 5 Å of ligands that were used for SASA calculations. (B) The averaged SASA (Å2) of the ligand-binding pockets in the T1R2 and T1R3 monomers calculated from the last 30 ns of three independent MD simulations. (C) The SASA (Å2) plot along the simulations. (D) The averaged total n(r) of all studied complexes. Data are expressed as mean ± SEM (n = 3).

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