Table 2 CVDs patients subdivided according to LV remodelling, LV hypertrophy associated to body fatness.

From: Dysfunctional EAT thickness may promote maladaptive heart remodeling in CVD patients through the ST2-IL33 system, directly related to EPAC protein expression

LV remodeling

Cardiovascular Patients (CVDs)

BMI

RTW (%)

LVM/BSA (g/m2)

EAT (mm)

Normal Geometry

13

26.84 ± 3.44

0.36 ± 0.05

90.69 ± 14.67

7.50 ± 2.20

Concentric Remodeling

2

27.65 ± 1.48

0.50 ± 0.06

106.50 ± 8.41

8.50 ± 0.70

Concentric Hypertrophy

18

25.86 ± 2.92

0.48 ± 0.08

155.80 ± 43.38

7.28 ± 2.64

Eccentric Hypertrophy

23

26.73 ± 3.80

0.37 ± 0.07

159.80 ± 56.44

6.95 ± 2.41

Normal Geometry

X BMI

RTW (%)

LVM/BSA (g/m2)

EAT (mm)

  

Spearman r

0.21

0.44

0.18

  

p

0.45

0.13

0.55

  

Concentric Hypertrophy

X BMI

RTW (%)

LVM/BSA (g/m2)

EAT (mm)

  

Spearman r

−0.08

0.11

0.21

  

p

0.75

0.66

0.48

  

Eccentric Hypertrophy

X BMI

RTW (%)

LVM/BSA (g/m2)

EAT (mm)

  

Spearman r

0.4

0.23

0.08

  

p

0.05

0.29

0.74

  
  1. To clarify better how body fat composition and LV mass geometry changes were linked, we divided the CVD population into four groups on the basis of the kind of remodeling: CVD patients with LV with normal geometry (RTW < 42%; LVM/BSA < 115 g/m2), with concentric remodeling (RTW ≥ 0.42%; LVM/BSA <115 g/m2), with LV mass with concentric hypertrophy (RTW ≥ 0.42%; LVM/BSA ≥ 115 g/m2) and eccentric hypertrophy (RTW < 0.42%; LVM/BSA ≥ 115 g/m2). Correlational results indicated a linear correlation with RTW in CVD patients with eccentric LV hypertrophy as one of the main indices of maladaptive heart remodeling, although the difference was close to significance (p = 0.05).
  2. BMI, body mass index; LVM/BSA, left ventricular mass on body surface area; RTW, relative wall thickness.
  3. All p less than 0.05 is considered statistically significative.
Back to article page