Table 1 Networks in which NBS revealed a negative effect of esketamine on dynamic rsFC.

Atlas	Statistic	p-value	Edges	Nodes
Esketamine < placebo
Exponentially weighted sliding-window
Craddock	Extent	0.004	45	36
Craddock	Intensity	0.002	45	36
Power	Extent	0.017	14	10
Power	Intensity	0.003	14	10
Power	Intensity	0.023	5	6
Multiplication of temporal derivatives
Craddock	Extent	0.033	25	19
Craddock	Extent	0.005	57	27
Craddock	Intensity	0.024	25	19
Craddock	Intensity	0.003	57	27
Power	Extent	0.005	23	23
Power	Intensity	0.005	23	23

Illustrates networks elucidated through NBS³¹. In these networks, regression coefficients between dynamic rsFC time-course and esketamine plasma levels differed significantly between the esketamine and placebo conditions, demonstrating a significant effect of esketamine on dynamic rsFC. All networks were found for the comparison esketamine < placebo.
Edges = number of connections, nodes = number of regions.
Exponentially weighted sliding-window based on Zalesky et al.²⁵, multiplication of temporal derivatives based on Shine et al.²⁶.
Craddock and Power denote parcellations based on Craddock et al.²⁹ and Power et al.³⁰.
Extent and intensity statistics based on NBS³¹.

Quick links

Search