Figure 1 | Scientific Reports

Figure 1

From: QCT-based finite element prediction of pathologic fractures in proximal femora with metastatic lesions

Figure 1

Graphical abstract of the project: Thirty-two paired femora (a) underwent QCT scanning (b) and elastic biomechanical experiments to determine stiffness (c). Based on clinical distribution in patients who suffered a pathologic fracture (d), metastatic lesions were simulated in either the superolateral or inferomedial neck in one femur of each pair (e), followed by a second QCT scan and stiffness test. All femora were then subjected to an ultimate biomechanical test to determine failure load11 (f). A FE model was generated based on geometry and bone density distribution (BV/TV) retrieved from QCT images (g). Experimental data were used to evaluate the QCT-based FE model (h).

Back to article page