Table 2 Association between SNP rs36023980 and clinical variables in SLE patients.
From: Evaluation of genetic susceptibility between systemic lupus erythematosus and GRB2 gene
Genotypic Tests | Allelic Tests | ||||||||
|---|---|---|---|---|---|---|---|---|---|
CC | CT | TT | *P | C | T | Chi | **P | **OR | |
Malar rash | |||||||||
Yes | 349 | 39 | 1 | 737 | 41 | ||||
No | 149 | 27 | 2 | 0.0745 | 325 | 31 | 4.8550 | 0.0325 | 1.69 |
Photosensitivity | |||||||||
Yes | 214 | 27 | 2 | 455 | 31 | ||||
No | 284 | 39 | 1 | 0.6939 | 607 | 41 | 0.0012 | 0.9925 | 1.00 |
Leucopenia | |||||||||
Yes | 197 | 24 | 1 | 418 | 26 | ||||
No | 301 | 42 | 2 | 0.8640 | 644 | 46 | 0.2987 | 0.5794 | 1.15 |
Anemia | |||||||||
Yes | 223 | 31 | 0 | 477 | 31 | ||||
No | 275 | 35 | 3 | 0.3615 | 585 | 41 | 0.0943 | 0.7562 | 1.08 |
Complement inhibition | |||||||||
Yes | 123 | 24 | 3 | 270 | 30 | ||||
No | 375 | 42 | 0 | 0.0030 | 792 | 42 | 9.1430 | 0.0030 | 0.48 |
Renal disorder | |||||||||
Yes | 243 | 36 | 2 | 522 | 40 | ||||
No | 255 | 30 | 1 | 0.5462 | 540 | 32 | 1.1060 | 0.3169 | 0.78 |
Neurologic disorder | |||||||||
Yes | 377 | 49 | 3 | 803 | 55 | ||||
No | 121 | 17 | 0 | 0.8466 | 259 | 17 | 0.0221 | 0.8610 | 0.95 |
Arthritis | |||||||||
Yes | 198 | 25 | 1 | 421 | 27 | ||||
No | 300 | 41 | 2 | 0.9090 | 641 | 45 | 0.1295 | 0.7212 | 1.09 |
Anti-dsDNA | |||||||||
Yes | 251 | 33 | 1 | 535 | 35 | ||||
No | 247 | 33 | 2 | 0.9607 | 527 | 37 | 0.0841 | 0.7846 | 1.07 |
Anti-RNP | |||||||||
Yes | 279 | 37 | 3 | 595 | 43 | ||||
No | 219 | 29 | 0 | 0.4333 | 467 | 29 | 0.3743 | 0.5522 | 0.86 |
Anti-Sm | |||||||||
Yes | 295 | 41 | 2 | 631 | 45 | ||||
No | 203 | 25 | 1 | 0.8665 | 431 | 27 | 0.2663 | 0.6143 | 0.88 |
Anti-SSA | |||||||||
Yes | 179 | 24 | 1 | 382 | 26 | ||||
No | 319 | 42 | 2 | 1.0000 | 680 | 46 | 0.0006 | 0.9898 | 1.00 |
Anti-SSB | |||||||||
Yes | 367 | 54 | 2 | 788 | 58 | ||||
No | 131 | 12 | 1 | 0.3085 | 274 | 14 | 1.4380 | 0.2337 | 0.70 |
