Table 3 The statistical analysis and nucleotide, amino acid mutations in the entire VP1 region of sub-genotype A1 among HFMD and AFP cases.
From: Multiple genotypes of Echovirus 11 circulated in mainland China between 1994 and 2017
Disease type | Total number of sequences of different sub-genotype | Nucleotide | Amino acid | Nucleotide | Amino acid | Nucleotide | Amino acid | |
|---|---|---|---|---|---|---|---|---|
A1 | D5 | 161/876* | 54/292* | 439/876* | 147/292* | 831/876* | 277/292* | |
HFMD | 16 | 5 | A → G | H → R | A → G | I → V | C → T | S → N |
AFP | 20 | 0 | 0 (0%) | 0 (0%) | 5 (31.25%) | 5 (31.25%) | 8 (50%) | 8 (50%) |
χ2(P) | 60.86 (P < 0.001) | 6 (30%) | 6 (30%) | 0 (0%) | 0 (0%) | 1 (5%) | 1 (5%) | |
