Figure 5

Estimating the contribution of biological factors to collagen abundance in IVD and articular cartilage. Forest plot for the estimated collagen abundance in IVD (a–c) and articular cartilage (d) as a function of sex (a), age (b), and tissue sub-location (c,d). Shown are subgroup averages and 95% CI as black dots/black lines, the overall effect sizes and 95% CI as black diamond, the number of datasets included within each subgroup is indicated in parenthesis. The size of the circle is proportional to the number of datasets; *indicates statistical significance.