Figure 4
From: TGF-β signaling promotes tube-structure-forming growth in pancreatic duct adenocarcinoma
Ultrastructural appearance of tubes and spheres. Cells were cultured in collagen (5 × 104 cells/mL) for 8 days and subjected to electron microscopic analysis. The images show (A) sphere-forming YamaPaca-6.12, (B) tube-forming YamaPaca-6.2, (C) 10 ng/mL TGF-β1-treated YamaPaca-6.12, and (D) 10 μM SB431542-treated YamaPaca-6.2 cells.
