Table 1 Comparison of TGF-β signaling target genes expressed in tube- and sphere-forming cancer cells.

From: TGF-β signaling promotes tube-structure-forming growth in pancreatic duct adenocarcinoma

Ratios of quantified mRNA expression*a

Number of genes

YamaPaca-6.2/YamaPaca-6.12

YamaPaca-25.1.1/YamaPaca-25.12

Same results between YamaPaca-6 and -25

Up

2.0<

11

25

6*b

Slight up

1.5–2.0

7

15

1

No change

0.75<, <1.5

55

36

NA

Slight down

0.5–0.75

8

2

1

Down

<0.5

2

5

0

Total

84

84

NA

  1. *aRatios were calculated according to the following formula: mRNA expression levels of tube-forming cells/mRNA expression levels of sphere-forming cells.
  2. *bThe names of the six genes are shown in Table 2.
Back to article page