Table 3 Cox Regression results in the Combined Cohort. Model 1 shows mutually adjusted HRs for IL-6 and IP-10.

From: A Pro-Inflammatory Biomarker-Profile Predicts Amputation-Free Survival in Patients with Severe Limb Ischemia

 

HR IL-6

95% CI

P-val

HR IP-10

95% CI

P-val

Model 1

1.47

1.22–1.77

3.0 e-5

1.41

1.16–1.73

0.0006

Model 2

1.45

1.20–1.75

9.2 e-5

1.46

1.19–1.78

0.0002

Model 3

1.4

1.15–1.70

0.0007

1.48

1.16–1.87

0.001

Model 4

1.35

1.06–1.71

0.01

1.49

1.13–2.00

0.006

  1. Model 2 shows adjusted HRs for Age and Sex. Model 3 is a fully adjusted model for Age, Sex, GFR, Presence of Diabetes, Hb, ABI, and Fontaine Classification. Model 4 is adjusted for the same factors as model 3, with the addition of CRP.