Table 1 Baseline clinical and biochemical characteristics of subjects with BMI > 25 kg/m2 and subjects with BMI < 25 kg/m2.
From: Genetic predictors of weight loss in overweight and obese subjects
Subjects with BMI < 25 kg/m2 (N = 168) | Subjects with BMI > 25 kg/m2 (n = 788) | p | ||
|---|---|---|---|---|
Age, years | 48.1 ± 14.05 | 59.01 ± 11.64 | <0.001 | |
Men, n (%) | 74 (48.7%) | 470 (59.7%) | 0.012 | |
Total cholesterol, mg/dL | 297 ± 47.3 | 294 ± 65.3 | 0.606 | |
Triglycerides, mg/dL | 232 ± 134 | 272 ± 321 | 0.208 | |
LDL-cholesterol, mg/dL | 205 ± 47.5 | 208 ± 60.4 | 0.228 | |
HDL-cholesterol, mg/dL | 53 ± 14.9 | 49.9 ± 19.6 | 0.008 | |
Glucose, mg/dL | 91.1 ± 25.2 | 98.8 ± 24.3 | 0.172 | |
Diabetes, n (%) | 8 (5.26%) | 156 (19.8%) | <0.001 | |
Hypertension, n (%) | 24 (15.8%) | 298 (37.9%) | <0.001 | |
APOE genotype, n (%) | ɛ3/ɛ3 | 116 (70.7%) | 504 (65.5%) | 0.346 |
ɛ3/ɛ4 | 34 (20.7%) | 159 (20.6%) | ||
ɛ3/ɛ2 | 9 (5.5%) | 70 (9.1%) | ||
ɛ2/ɛ4 | 1 (0.6%) | 10 (1.3%) | ||
ɛ4/ɛ4 | 4 (2.4%) | 16 (2.1%) | ||
ɛ2/ɛ2 | 0 | 11 (1.4%) | ||
