Table 2 Baseline values and variation in clinical and biochemical characteristics comparing groups based on the weight change that the subjects experienced during the follow-up.

From: Genetic predictors of weight loss in overweight and obese subjects

 

Subjects who lost more than 2% body weight (N = 258)

Subjects who varied by less than 2% body weight (N = 335)

Subjects who gained more than 2% body weight (N = 194)

p

Age, years

59.8 ± 11.9

59.4 ± 11.3

57.3 ± 11.7

0.055

Men, n (%)

145 (56.2%)

205 (61.2%)

121 (62.4%)

0.334

Baseline weight, kg

83.3 ± 13.1

79.4 ± 11.3

80.0 ± 12.8

<0.001

Baseline BMI, kg/m2

30.2 ± 3.37

28.4 ± 2.74

28.5 ± 2.73

<0.001

Baseline waist circumference, cm

104 ± 9.15

97.8 ± 8.75

98.7 ± 9.70

<0.001

Baseline fat mass, kg

27.3 ± 7.89

23.6 ± 6.30

24.1 ± 6.29

<0.001

Baseline muscle mass, kg

51.5 ± 10.9

50.4 ± 10.9

50.7 ± 11.5

0.736

Baseline bone mass, kg

2.73 ± 0.51

2.71 ± 0.49

2.71 ± 0.53

0.921

Baseline visceral fat level, %

11.9 ± 3.74

10.8 ± 3.52

10.8 ± 3.53

0.014

Baseline cholesterol, mg/dL

287 ± 62.1

293 ± 61.2

306 ± 74.9

0.014

Baseline triglycerides, mg/dL

281 ± 384

260 ± 271

282 ± 308

0.284

Baseline HDLc, mg/dL

49.6 ± 26.1

49.9 ± 13.7

50.1 ± 18.2

0.244

Baseline glucose, mg/dL

101 ± 27.3

96.9 ± 20.7

99.0 ± 25.7

0.007

Baseline energy consumption, Kcal/day

2299,6 ± 632

2303 ± 615

2294 ± 635

0.996

Baseline carbohydrate consumption, g/day

259 ± 91.1

256 ± 87.3

258 ± 92.1

0.983

Baseline protein consumption, g/day

94.6 ± 23.2

92.8 ± 21.8

91.8 ± 23.0

0.713

Baseline fat consumption, g/day

88.5 ± 25.5

89.6 ± 25.7

88.7 ± 26.8

0.972

Weight change after one year, %

−5.76 ± 4.06

−0.03 ± 1.14

4.60 ± 2.67

<0.001

Waist circumference change, cm

−0.88 ± 9.26

2.60 ± 6.38

5.20 ± 7.40

<0.001

Change in fat mass, %

−7.02 ± 18.1

3.65 ± 28.0

8.84 ± 20.9

<0.001

Change in muscle mass, %

0.07 ± 16.4

3.73 ± 20.3

4.52 ± 20.9

<0.001

Change in visceral fat level, %

−1.09 ± 19.1

7.32 ± 16.6

11.8 ± 17.2

<0.001

Change in cholesterol, %

−28.3 ± 19.2

−28.0 ± 22.3

−29.6 ± 21.9

0.605

Change in triglycerides, %

−13.8 ± 51.2

−13.9 ± 46.5

−5.59 ± 69.3

0.442

Change in HDLc, %

18.0 ± 132

8.99 ± 23.4

7.17 ± 27.5

0.037

Change in glucose, %

11.4 ± 77.2

8.13 ± 62.4

7.40 ± 20.4

0.241

  1. Quantitative variables are expressed as the means ± standard deviations. The p values were calculated by the ANOVA test or the Kruskal-Wallis test, as appropriate.