Figure 4 | Scientific Reports

Figure 4

From: Temporin L and aurein 2.5 have identical conformations but subtly distinct membrane and antibacterial activities

Figure 4

Interaction of aurein 2.5 with lipid bilayers in silico. Examples of peptides aggregating as a dimer or a trimer are shown respectively for POPE/POPG (A) and POPG (D) simulations. Basic, polar, acidic and hydrophobic residues are coloured in blue, green, red and white respectively with lipids and water removed for clarity. The top view snapshot shows the tendency to aggregate for the eight peptides in POPE/POPG (B) or POPG (E). Heatmaps of average inter-peptide Cα-Cα distances, in Angstroms, for peptides in POPE/POPG (C) or POPG (F) show the stronger interactions that mediate assembly of aggregates.

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