Table 1 Baseline characteristics of patients stratified according to the sPD-L1 level.

From: Prognostic implications of soluble programmed death-ligand 1 and its dynamics during chemotherapy in unresectable pancreatic cancer

Variable

sPD-L1 < 4.6 ng/mL (N = 52)

sPDL1 ≥ 4.6 ng/mL (N = 8)

P-value

Age, years

≥60

23 (44.2)

2 (25.0)

0.449

<60

29 (55.8)

6 (75.0)

Sex

Male

31 (59.6)

2 (25.0)

0.124

Female

21 (40.4)

6 (75.0)

Disease extent

Locally advanced

13 (25.0)

1 (12.5)

0.667

Metastatic

39 (75.0)

7 (87.5)

CA19-9, U/mL

Elevated (≥37.0)

39 (75.0)

8 (100.0)

0.182

Decreased (<37.0)

13 (25.0)

0 (0.0)

Total bilirubin, mg/dL

Elevated (>1.2)

12 (23.1)

0 (0.0)

0.338

Normal (≤1.2)

40 (76.9)

8 (100.0)

Albumin, g/dL

Normal (≥3.3)

49 (94.2)

8 (100.0)

1.000

Decreased (<3.3)

3 (5.8)

0 (0.0)

NLR

Increased (≥1.83)

41 (78.8)

5 (62.5)

0.374

Decreased (<1.83)

11 (21.2)

3 (37.5)

 

NLR

Mean

3.00 (±1.55)

2.97 (±1.70)

0.940

PLR

Increased (≥109.6)

37 (71.2)

6 (75.0)

1.000

Decreased (<109.6)

15 (28.8)

2 (25.0)

 

PLR

Mean

156.6 (±60.01)

171.8 (±72.55)

0.388

  1. Abbreviations: cancer antigen 19-9 = CA 19-9; NLR = neutrophil-to-lymphocyte ratio; PLR = platelet-to-lymphocyte ratio; and sPD-L1 = soluble programmed death-ligand 1.