Table 1 Patient characteristics of the training and validation cohorts.
From: Serum PlGF and EGF are independent prognostic markers in non-metastatic colorectal cancer
Training cohort (n = 219) | Validation cohort (n = 168) | p | |
|---|---|---|---|
n (%); mean (SD) | n (%); mean (SD) | ||
Sex | |||
Male | 127 (58.0) | 102 (70.7) | 0.598 |
Female | 92 (42.0) | 66 (39.3) | |
Age [years] | 67.0; 11.1 | 67.0; 10.8 | 0.650 |
≤70 | 137 (62.6) | 107 (63.7) | 0.819 |
>70 | 82 (37.4) | 61 (36.3) | |
Body mass index [kg/cm 2 ] | |||
≤25 | 77 | 76 | 0.612 |
>25 | 104 | 92 | |
Site of disease | |||
Colon | 106 (48.4) | 72 (42.9) | 0.278 |
Rectum | 113 (51.6) | 96 (57.1) | |
Surgical procedure | |||
(Ext.) right hemicolectomy | 49 (22.4) | 41 (24.4) | |
Transvere colon resection | 1 (0.5) | 1 (0.6) | |
(Ext.) left hemicolectomy | 24 (11.0) | 15 (8.9) | |
Sigmoid resection | 13 (5.9) | 15 (8.9) | |
Anterior rectal resection | 109 (49.7) | 83 (49.4) | |
Rectal extirpation | 9 (4.1) | 11 6.5) | |
Others | 14 (6.4) | 2 (1.2) | |
Neoadjuvant therapy | |||
Yes | 47 (21.5) | 43 (25.6) | 0.340 |
No | 172 (78.5) | 125 (74.4) | |
pT | |||
pT0/pTis | 1 (0.5) | 3 (1.8) | 0.198 |
pT1 | 22 (10.0) | 14 (8.3) | |
pT2 | 68 (31.1) | 42 (25.0) | |
pT3 | 113 (51.6) | 101 (60.1) | |
pT4 | 15 (6.8) | 8 (4.8) | |
pN | |||
N0 | 134 (61.2) | 109 (64.9) | 0.411 |
N1 | 54 (24.7) | 40 (23.8) | |
N2 | 31 (14.2) | 18 (10.7) | |
Nx | 0 | 1 (0.6) | |
cM | |||
0 | 219 (100) | 168 (100) | — |
1 | 0 | 0 | |
UICC stage | |||
I | 69 (31.5) | 45 (26.8) | 0.386 |
II | 65 (29.7) | 65 (38.7) | |
III | 85 (38.8) | 58 (34.5) | |
Grade | |||
1 | 0 | 0 | 0.498 |
2 | 5 (2.3) | 2 (1.2) | |
3 | 155 (70.8) | 115 (68.5) | |
4 | 44 (20.1) | 25 (14.9) | |
x | 15 (6.8) | 26 (15.4) | |
