Figure 1

Effects of steroid compounds on the gentle touch response of wild type and nhr-69∆. Positive (upturned triangles) or negative reactions (downturned triangles) of C. elegans (a,b) wild type or (c,d) nhr-69∆ worms to successive tactile stimuli applied either to the (a,c) head (anterior) or (b,d) tail region (posterior) of L4 worms that had developed from egg to this larval stage under control (green symbols and lines) or five test conditions (exposures to testosterone, ADD, 7α-HADD, 12β-HADD, or 12β-DHADD) (mean ± sd; per experimental condition, n ≥ 60 different worms). Asterisks indicate significance levels (**P < 0.01; two-way anova and subsequent Student-Newman-Keuls analysis).