Table 2 Pearson’s correlations analysis of urinary exosomal miR-21-5p, miR-30b-5p, let-7e-5p, miR-23b-3p and miR-125b-5p expression and clinical parameters in the validation cohort.

Parameter	miR-21-5p		miR-30b-5p		let-7e-5p		miR-23b-3p		miR-125b-5p
Parameter	r	p value	r	p value	r	p value	r	p value	r	p value
Age	0.180	0.267	−0.148	0.362	0.209	0.195	0.196	0.226	−0.110	0.498
Gender^Ɨ	−0.041	0.801	<0.001	1.000	0.063	0.700	0.017	0.915	0.022	0.894
SBP	−0.013	0.936	−0.075	0.652	−0.036	0.827	0.001	0.994	0.187	0.254
DBP	−0.231	0.158	0.202	0.217	−0.275	0.090	−0.316	0.050	0.180	0.274
HDL-C	−0.298	0.087	0.427	0.012	−0.289	0.097	−0.247	0.159	0.059	0.742
LDL-C	0.020	0.913	−0.045	0.802	−0.020	0.910	0.005	0.978	0.132	0.464
Total cholesterol	−0.117	0.504	−0.041	0.813	−0.100	0.570	−0.052	0.768	−0.049	0.782
Serum creatinine	0.517	<0.001	−0.430	0.006	0.392	0.012	0.298	0.062	−0.092	0.574
HbA1c	0.111	0.633	−0.191	0.406	0.030	0.896	0.106	0.647	−0.007	0.978
eGFR	−0.334	0.035	0.299	0.060	−0.224	0.164	−0.164	0.311	0.093	0.566
ACR	0.039	0.811	−0.071	0. 664	0.055	0.738	0.027	0.868	0.391	0.013
CVD^Ɨ	0.035	0.831	−0.157	0.334	0.096	0.557	0.150	0.355	−0.024	0.883

SBP: systolic blood pressure; DBP: diastolic blood pressure; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; HbA1c: glycosylated haemoglobin; eGFR: estimated glomerular filtration rate; ACR: urinary albumin-to-creatinine ratios; CVD: cardiovascular disease. ^ƗSpearman’s correlation analysis.

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