Table 3 Binding affinity of KLK4 inhibitors to KLK4.

From: A protein scaffold, engineered SPINK2, for generation of inhibitors with high affinity and specificity against target proteases

ID

kon (M−1 s−1)

koff (s−1)

KD (pM)

K40001

6.99 × 106

1.45 × 10−5

2.08

K40003

4.40 × 106

1.02 × 10−4

23.2

K41043

1.16 × 107

1.03 × 10−4

8.91

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