Figure 4 | Scientific Reports

Figure 4

From: Structural basis for the inhibitory effects of a novel reversible covalent ligand on PPARγ phosphorylation

Figure 4

Superposition of SB1495 and SB1494 with other PPARγ ligands from known complex structures. A total of 138 ligand-bound PPARγ LBD structures in PDB were superposed onto the SB1495-bound structure (bright orange). Green and cyan ball-and-stick models indicate SB1495 and SB1494, respectively, and blue lines represent the other ligands. Right panel shows a magnified image of PPARγ LBP. Characteristic ligand-binding regions Arm1, Arm2, and Arm3 in PPARγ LBP are highlighted in red circles.

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