Figure 6

The magnified image of interactions between SB1495 and helix H2′ of PPARγ. SB1495 and SB1494 are represented by green and cyan ball-and-stick models, respectively. Glu259 and Arg280 that form hydrogen bonds in the SB1495-bound structure are shown as bright orange ball-and-stick models. Oxygen and nitrogen atoms are colored in red and blue, respectively. Dashed lines depict hydrogen bonds and the corresponding hydrogen bond distances (Å) are labeled.