Figure 3

Tibia cortical bone geometry changes. The illustration shows that the cortical bone of the tibial midshaft differs in geometry between sham and surgery mice. In the cross-sectional view (excluding the shaft), the marrow area (M.Ar) is in green, the bone area (B.Ar) is in blue, and the tissue area (T.AR) is the combination of the marrow area and bone area (blue + green). Although figure dimensions are exaggerated for visual understanding, the relationship as quantified by µCT data between sham (M.Ar, B.Ar, and T.Ar) and surgery (M.Ar’, B.Ar’, and T.Ar’) areas is as follows: M.Ar’ = 2M.Ar, B.Ar’ = B.Ar, and T.Ar’ = 1.3T.Ar. These images were adapted from Servier Medical Art with permission (http://smart.servier.com/).