Figure 2
Immunohistochemistry (IHC) of different tissue sections of variegated squirrel bornavirus 1 (VSBV-1) infected variegated and Prevost’s squirrels demonstrating a wide-spread tissue distribution. (A) Nose of variegated squirrel V#3. Demonstration of VSBV-1 P in the olfactory epithelium; original magnification x400. (B) Lung, bronchus of Prevost’s squirrel P#2. VSBV-1 P in bronchial epithelium and cells with alveolar macrophage-morphology (insert, arrows); original magnification x400. (C) Large intestine of Prevost’s squirrel P#3. VSBV-1 P in the plexus myentericus; original magnification x400. (D) Kidney of variegated squirrel V#6. VSBV-1 P in a patchy distribution pattern; VSBV-1 P in Bowman capsule and podocytes of glomeruli and in tubular epithelium (insert); original magnification x100, magnification of insert x400. (E) Skin of Prevost’s squirrel P#7. VSBV-1 P in epithelium, sebaceous glands (arrow), hair follicles, and skin nerves (arrowhead); original magnification x100. (F) Lacrimal gland of Prevost’s squirrel P#8. VSBV-1 P in the epithelium of acini and intralobular ducts; original magnification x100.
