Figure 5 | Scientific Reports

Figure 5

From: ANO5 mutations in the Polish limb girdle muscular dystrophy patients: Effects on the protein structure

Figure 5

Eigenvector analysis. Plot of eigenvalues corresponding to the eigenvector index for the first 10 modes of motion in the PCA-1 (in (A)) or PCA-2 (in (B)) analyses carried out for the wild-type and mutant ANO5 dimer structures. (C), time development of projections of 2 features (distance-dependent functions) obtained from PCA-3 analysis of the central α-helices at the dimerization interface in the wild-type and mutant ANO5 structures. Color legend in (C) ANO5, black; p.Asp81Gly, red; p.Lys132Met, green; p.Ser555Ile, blue; p.Tyr671Cys, cyan; p.Arg758Cys, magenta; and p.His841Asp, orange.

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