Table 3 Subgroup analysis of the included study.
Subgroup | Studies | Sensitivity (95%) | Specificity (95%) | PLR (95%) | NLR (95%) | DOR | AUC | |
|---|---|---|---|---|---|---|---|---|
World bank income classification | HIC | 5 | 0.71 (0.63,0.79) | 0.94 (0.87,0.98) | 7.99 (2.68,23.86) | 0.35 (0.23,0.51) | 33.69 (6.78,167.49) | 0.8277 |
UMIC | 10 | 0.72 (0.67,0.77) | 0.80 (0.75,0.84) | 3.91 (2.27,6.74) | 0.32 (0.20,0.51) | 14.79 (5.98,36.60) | 0.8576 | |
IP-10 | TB Ag | 7 | 0.71 (0.65,0.77) | 0.85 (0.80,0.90) | 6.11 (2.20,17.02) | 0.30 (0.16,0.58) | 24.66 (5.15,118.18) | 0.8456 |
Unstimulated | 8 | 0.73 (0.67,0.79) | 0.81 (0.75,0.86) | 4.08 (2.31,7.19) | 0.34 (0.22,0.51) | 15.36 (8.64,27.30) | 0.8651 | |
Study design | Cohort | 8 | 0.75 (0.68,0.81) | 0.76 (0.69,0.82) | 3.40 (2.02,5.73) | 0.34 (0.23,0.49) | 12.09 (6.09,24.01) | 0.8377 |
Case control | 6 | 0.73 (0.67,0.78) | 0.88 (0.82,0.92) | 6.69 (2.22,20.17) | 0.28 (0.14,0.58) | 29.15 (5.07,167.71) | 0.8773 | |
Cross section | 1 | — | — | — | — | — | — | |
HIV-infected | Yes or some | 2 | 0.81 (0.58,0.95) | 0.90 (0.78,0.97) | 9.52 (0.78,116.35) | 0.24 (0.06,0.97) | 53.54 (1.19,2403.79) | — |
No | 10 | 0.70 (0.65,0.75) | 0.87 (0.82,0.91) | 5.33 (2.79,10.19) | 0.33 (0.21,0.52) | 19.31 (6.76,55.15) | 0.8916 | |
Not reported | 3 | 0.77 (0.67,0.86) | 0.68 (0.58,0.78) | 2.44 (1.15,5.18) | 0.31 (0.21,0.47) | 9.97 (3.20,31.08) | 0.85 | |
Cut-off | <2000 pg/ml | 8 | 0.73 (0.66,0.78) | 0.78 (0.71,0.84) | 3.63 (2.07,6.37) | 0.35 (0.24,0.50) | 12.10 (6.19,23.65) | 0.8343 |
≥2000 pg/ml | 7 | 0.71 (0.65,0.77) | 0.88 (0.82,0.92) | 6.38 (2.50,16.28) | 0.31 (0.16,0.59) | 25.64 (5.63,116.77) | 0.8811 | |
