Table 1 Metabolic characteristics of the mice after HFD-feeding for nine weeks (second mouse study).

From: Extended indirect calorimetry with isotopic CO2 sensors for prolonged and continuous quantification of exogenous vs. total substrate oxidation in mice

Parameter

Outcome

BW (g)a

31.57 (24.82, 38.22)

FM (g)a

10.21 (5.52, 15.88)

LM (g)a

19.89 (17.68, 21.64)

FM gain (g)b

8.66 (4.41, 14.06)

FI (g)b

188.38 (161.67, 226.33)

24 h EE (kJ d–1)c

44.24 (38.66, 51.45)

24 h RERc

0.81 (0.74, 0.89)

∆RER (RER44 – RER0)c

0.16 (0.10, 0.20)

Fasting glucose (mmol l–1)a

6.0 (4.9, 7.2)

Fasting insulin (ng ml–1)a

2.65 (0.85, 8.95)

Postprandial glucose (mmol l–1)a

6.9 (3.3, 9.1)

Postprandial insulin (ng ml–1)a

4.40 (1.47, 9.22)

  1. aMeasured in PW 15 (end of HFD). bMeasured from PW 7 (start of HFD) to PW 15. cMeasured in PW 14–15. HFD, high-fat diet; BW, body weight; FM, fat mass; LM, lean mass; FI, food intake; EE, energy expenditure; RER, respiratory exchange ratio (mean of 24 h). Data is presented as means and range, n = 48 (except ∆RER, n = 47; fasting glucose and insulin n = 24; and postprandial glucose and insulin, n = 23).
Back to article page