Table 1 Effect of variation in experimental parameters on the physicochemical properties of the nanoemulsions prepared by self-emulsification.
From: Self-assembled hyaluronan nanocapsules for the intracellular delivery of anticancer drugs
Formulation variables | NEs characterization* | ||
|---|---|---|---|
Solutol®HS15 conc. (mg/mL) | Miglyol®812/Tween®80 ratio (w/w) | Oil/aq. phase ratio (v/v) | Size (nm) |
2.5 | 1:1 | 1:2 | 138 ± 3 |
5 | 138 ± 2 | ||
15 | 149 ± 3 | ||
25 | 140 ± 1 | ||
2.5 | 1:1 | 1:2 | 138 ± 3 |
1.5 :1 | 147 ± 3 | ||
2 :1 | 164 ± 1 | ||
3.5 :1 | 159 ± 3 | ||
2.5 | 1:1 | 1:3 | 139 ± 2 |
1:4 | 144 ± 1 | ||
1:5 | 152 ± 3 | ||
1:8 | 138 ± 3 | ||