Figure 1

Microbead injection increases SM IOP. (a) IOP measurements in awake SMs prior to and after intracameral microbead injection (dots). Black dots represent MOM injections required to elevate IOP. Grey dots represent re-injection (one SM/dot) when IOP in that SM appeared to be decreasing. *p < 0.008 from week 8 to end of study, n = 7 eyes for saline and microbead. (b) Bar graph showing mean IOP in saline- and microbead-injected eyes. *p = 0.00003, n indicated in bars. (c) Representative post-mortem images of microbeads in the anterior chamber (top) and along the iridocorneal angle following dissection of the cornea (bottom). Data are expressed as mean ± SEM. Statistical comparisons were made using two-sided t-tests.