Figure 1

ACh stimulates and tiotropium inhibits MP generation. (A,B) dose response of the effect of ACh stimulation for 16HBE (A) and HUVEC (B). (C,D) dose-response of the effect of tiotropium on ACh-induced generation of MP by 16HBE cells (C) and HUVEC (D). Data are mean ± SEM from 3 consecutive experiments.