Figure 5

Schematic representation of the secondary structure of the lowest-energy solution structure of LC3C (similar view as in Fig. 2) colored according to the backbone amide 15N chemical shift change between the major (population 98.37% ± 0.06%) and the minor (population 1.63% ± 0.06%) state, |ΔϖN|, from 0.00 ppm (blue) to 6.00 ppm (red), or blue if ΔϖN could not be determined due to missing resonance assignments, resonance overlap, or if the exchange contributions to transverse relaxation were of insufficient magnitude. Values of |ΔϖN| > 1.5 ppm (green to red) are localized to specific regions, indicating that the rest of the tertiary structure is not affected by the conformational exchange process. The figure was drawn with MolScript 2.1.2100 and rendered with Raster3D 3.0101.