Figure 2

Stratification of rheumatoid arthritis patients according to serum titres of RF and ACPAs. (a) Patient characteristics amongst the four sera sub-types. (b) RF titres determined by IgG1 Fc-based ELISA for the four sera sub-types. Threshold for RF+ was set at 20 U/mL (red line). (c) ACPA titres determined by citrullinated protein-based ELISA for the four sera sub-types. Threshold for ACPA+ was set at 5 U/mL (red line).