Table 1 Different antiadhesive excipients effects on the total time required for the unfolding process (pH 1.2).
From: Development of Gabapentin Expandable Gastroretentive Controlled Drug Delivery System
Antiadhesive excipient | Length of the tested layer(mm) | |
|---|---|---|
After 10 minutes | After 15 minutes | |
Talc | 12 | 12 |
Microcrystalline cellulose | —* | — |
Starch | 10 | 12 |
Magnesium stearate | — | — |
Magnesium stearate and talc | — | — |
Magnesium stearate, citric acid and sodium bicarbonate | — | — |
Talc, citric acid and sodium bicarbonate | 18 | 20 |
Citric acid and sodium bicarbonate | 21 | 24 |
