Table 4 Associations of serum GGT level with increased total IgE levels and IgE sensitization by sex.

From: Sex difference in IgE sensitization associated with alcohol consumption in the general population

GGT

Male

Female

T1†

T2†

T3†

T1†

T2†

T3†

Numbers (%)

311 (33.9)

303 (33.0)

304 (33.1)

300 (37.3)

250 (31.0)

255 (31.7)

Crude OR

Total IgE

1

1.36 (0.93–1.98)

2.13 (1.44–3.16)*

1

1.20 (0.70–2.05)

1.73 (1.05–2.83)*

DF

1

1.01 (0.67–1.52)

1.33 (0.92–1.92)

1

1.21 (0.78–1.86)

0.97 (0.63–1.49)

Cockroach

1

1.11 (0.68–1.83)

1.75 (1.17–2.62)*

1

2.41 (1.27–4.53)*

1.74 (0.89–3.83)

Dog

1

1.32 (0.62–2.81)

1.39 (0.71–2.72)

1

0.94 (0.32–2.72)

1.07 (0.39–2.93)

Atopy

1

1.04 (0.68–1.57)

1.44 (0.99–2.11)

1

1.08 (0.71–1.64)

0.91 (0.58–1.43)

Adjusted OR ‡

Total IgE

1

1.49 (0.91–2.40)

2.73 (1.72–4.33)*

1

1.25 (0.62–2.51)

1.24 (0.62–2.48)

DF

1

1.25 (0.76–2.06)

2.17 (1.35–3.47)*

1

1.07 (0.58–1.99)

0.92 (0.49–1.71)

Cockroach

1

0.75 (0.45–1.26)

1.25 (0.77–2.03)

1

2.02 (0.88–4.63)

1.62 (0.73–3.61)

Dog

1

2.25 (0.66–7.72)

2.86 (0.99–8.25)

1

2.31 (0.51–10.50)

3.67 (0.92–14.64)

Atopy

1

1.07 (0.67–1.69)

2.01 (1.28–3.15)*

1

0.87 (0.49–1.55)

0.95 (0.52–1.74)

  1. †Sex-specific GGT tertiles based on their serum levels. In males, cut-off points were <25 IU/L (T (tertile) 1), 25 to 43 IU/L (T2), and >43 IU/L (T3). In females, the cut-off points were <14 IU/L (T1), 14 to 18 IU/L (T2), and >18 IU/L (T3).
  2. ‡Multivariable adjustment for age, residential area, educational level, marital status, household income, occupation, smoking status, exercise status, sleep duration, obesity, vitamin D levels and allergic diseases.
  3. DF: Dermatophagoides farinae; GGT: gamma-glutamyl transferase; OR: odds ratio.
  4. *p < 0.05.
  5. The English in this document has been checked by at least two professional editors, both native speakers of English. For a certificate, please see: http://www.textcheck.com/certificate/J8ex65.
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