Table 1 The composition of DEG modules of BRCA, including the number of DEGs, the number of effective DEGs, the dominant SGAs, and the proportion of co-regulations produced by each dominant SGA.
From: Tumour-specific Causal Inference Discovers Distinct Disease Mechanisms Underlying Cancer Subtypes
Module Index | # of DEG | # of Effective DEGs | Dominant SGAs (Prop. of Co-regulation) |
|---|---|---|---|
Module 1 | 288 | 259 | CDH1 (60.2%), GATA3 (20.8%), PIK3CA (12.4%) |
Module 2 | 225 | 202 | PTEN (66.1%), PIK3CA (19.6%) |
Module 3 | 155 | 138 | ZFHX4 (44.7%), RYR2 (22.9%) |
Module 4 | 302 | 281 | GATA3 (92.7%) |
Module 5 | 214 | 184 | ERBB2 (58.0%), PIK3CA (17.4%) |
Module 6 | 135 | 124 | TP53 (96.4%) |
Module 7 | 428 | 387 | PIK3CA (90.5%) |
