Figure 3

Screening activators of Bdnf transcription from an herbal extract library. Representative results obtained using an herbal extract library consisting of 120 herbal extracts. Each extract was added into Bdnf-Luc cortical cells at 13 DIV at a final concentration of 500 μg/mL. Luciferase activity was measured in each well at 6 h (a), 24 h (b), or 48 h (c) after addition of extract. Means ± SEM (n = 3). Active extracts (that increased Bdnf induction by more than 2-fold) are shown in red.