Figure 8
From: The genetic relationship between female reproductive traits and six psychiatric disorders
Genetic correlations between the five reproductive traits and the six psychiatric disorders estimated using the base model. Color of each box represents the level of estimated genetic correlation (blue for positive and red for negative correlation), and the size of squares represents its significance (p-value). Estimated genetic correlations that are significantly different from zero after Bonferroni correction (0.05/30) are marked with an asterisk. AFB: Age at first birth. AFS: Age at first sexual intercourse. AMC: Age at menarche. AMP: age at menopause. NLB: Number of live births. ADHD: Attention-Deficit/Hyperactivity Disorder. ASD: Autism spectrum disorder. ED: Eating disorder. BIP: Bipolar disorder. MDD: Major depressive disorder. SCZ: Schizophrenia. In the base model, the reproductive traits were adjusted for age at interview, year of birth, study center, genotype batch, and the first 15 principal components.
