Table 1 Five most highly dysregulated circRNAs in Alzheimer’s disease model.
From: Possible epigenetic regulatory effect of dysregulated circular RNAs in Alzheimer’s disease model
circRNA name | Type* | Best related linear transcript (Gene symbol) | Fold change | P value |
|---|---|---|---|---|
7 M Up-regulated | ||||
mmu_circRNA_28972 | exonic | NM_025730 (Lrrk2) | 3.540 | 0.001 |
mmu_circRNA_28971 | exonic | NM_025730 (Lrrk2) | 3.528 | 0.004 |
mmu_circRNA_29980 | overlapping | NM_007471 (App) | 2.351 | 0.001 |
mmu_circRNA_35502 | exonic | NM_019918 (Vmn2r1) | 2.320 | 0.041 |
mmu_circRNA_39081 | exonic | NM_010097 (Sparcl1) | 1.992 | 0.030 |
7 M Down-regulated | ||||
mmu_circRNA_22066 | exonic | NM_172788 (Sh3rf3) | 2.056 | 0.035 |
mmu_circRNA_001769 | exonic | NR_046233 (Rn45s) | 1.872 | 0.030 |
mmu_circRNA_30284 | overlapping | NM_001104569 (Vmn2r107) | 1.844 | 0.028 |
mmu_circRNA_011516 | exonic | ENSMUST00000023060 (Npcd) | 1.823 | 0.037 |
mmu_circRNA_19403 | exonic | ENSMUST00000050472 (Uspl1) | 1.758 | 0.007 |
12 M Up-regulated | ||||
mmu_circRNA_29980 | intronic | NM_007471 (App) | 2.753 | 0.035 |
mmu_circRNA_45982 | exonic | NM_010797 (Mid1) | 2.102 | 0.025 |
mmu_circRNA_23412 | exonic | NM_028451 (Larp1) | 1.594 | 0.049 |
mmu_circRNA_19523 | intronic | NM_172536 (Zfp609) | 1.590 | 0.032 |
mmu_circRNA_012412 | overlapping | NR_046233 (Rn45s) | 1.508 | 0.027 |
12 M Down-regulated | ||||
mmu_circRNA_34884 | exonic | NM_001291137 (Ralgapb) | 1.602 | 0.038 |
mmu_circRNA_008816 | exonic | NM_027436 (Mipep) | 1.601 | 0.031 |
mmu_circRNA_37345 | exonic | NM_011327 (Scp2) | 1.556 | 0.043 |
mmu_circRNA_45069 | exonic | NM_153413 (Dock3) | 1.516 | 0.048 |
mmu_circRNA_35843 | exonic | NM_013841 (Vps45) | 1.512 | 0.035 |
