Figure 7
From: A comprehensive computational study of amino acid interactions in membrane proteins
Sulfur-π interactions between Met or Cys and Phe, Tyr or Trp. (a) Energy profile (in kcal/mol) as a function of the interresidue distance d (in Å) in globular proteins (dashed black), extramembrane (blue) and in the transmembrane regions (red). (b) Energy profile for sulfur-π (small dashed red), π-π (large dashed red) and sulfur-sulfur (continuous red) interactions in the transmembrane regions. (c) Example of sulfur-π interaction in the transmembrane region of the PDB structure 3S8G (ba3 cytochrome c oxidase); Met and Cys are in yellow and aromatic residues in magenta.
